Enabling Novel Tracers for MRI and NMR

Need:
The development of new contrast agents or tracers for MRI is vital for advancing healthcare, research, and diagnostics, allowing for more accurate and detailed imaging and insights into various biological processes and diseases.
These novel tracers should allow to perform NMR/MRI scans in lower magnetic fields, shorter time, or with a higher signal-to-noise ratio, and/or study samples and medical conditions that were challenging or impossible to address with NMR/MRI until now.
Goal:
The project aims to address the low sensitivity of Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) with a cheap, compact, and versatile setup based on the dynamic nuclear polarisation (DNP) technique used in polarised targets for particle physics experiments.
The team proposes to enhance the sensitivity of NMR/MRI on stable nuclei by up to 10 000. When applied to unstable nuclei, it will offer an additional enhancement of 100 000 by enabling radiation-detected (RD) NMR/MRI, actively developed at ISOLDE, in which signals are observed as asymmetric emission of decay radiation.
This proposal also aims to find an alternative for polarising both stable and unstable nuclei. These developments will happen in parallel to the ZULF-NMR project, allowing CERN to have full control of the technology and not be dependent on external partners.